Juventus forward Mario Mandzukic is fit again after an ankle problem ruled him out of the fixture against Cagliari at the weekend.
Midfielders Douglas Costa and Emre Can, winger Federico Bernardeschi and forward Moise Kean are not available.
Coach Massimiliano Allegri said he might select Juan Cuadrado, Paulo Dybala and former United player Cristiano Ronaldo as a three-pronged attack.
Juventus are top of Champions League Group H with three wins from three. They also lead Serie A by six points after a record-breaking start to the campaign, winning their first 10 matches in all competitions.
— JuventusFC (@juventusfc) November 7, 2018
The stage is set 🏟👌
— JuventusFC (@juventusfcen) November 7, 2018